This paper explains the reasons and purposes of the work which was undertaken in Italy on seismic isolation and gives the main features and some first results of the experimental activities. These activities are (a) the static and dynamic experiments which were carried out in the framework of acceptance tests of the high damping steel-laminated elastomer bearings used in the first group of large isolated buildings existing in Italy (Administration Center of the SIP Telephone Company at Ancona), and (b) the tests which are in progress to support the development of qualification procedures for seismic isolation of industrial plants, including the innovative nuclear reactors. Furthermore, the paper provides information on the efforts which have been undertaken in Italy to promote and coordinate studies on seismic isolation in the various domains of possible application.