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Laser-assisted fabrication of biomolecular sensing microarrays

TitoloLaser-assisted fabrication of biomolecular sensing microarrays
Tipo di pubblicazioneArticolo su Rivista peer-reviewed
Anno di Pubblicazione2007
AutoriGagliardi, S., Rapone B., Mosiello Lucia, Luciani D., Gerardino A., and Morales P.
RivistaIEEE Transactions on Nanobioscience
Volume6
Paginazione242 - 248
Data di pubblicazione2007///
Parole chiaveAtomic force microscopy, Biosensors, Microarrays, Nanofabrication, Pulsed laser deposition
Abstract

With the aim of obtaining high density biosensing arrays we use pulsed laser deposition to immobilize functional biomolecules on useful surfaces, and micro- and nanopatterning techniques for fabrication of prototype immunosensing bioarrays. We report biological activity tests demonstrating the functional properties of the immobilized proteins and atomic force microscopy characterization of films of nanometric dimensions. Laser-fabricated immunofluorescent arrays are analyzed to check that the intensity and contrast of the sensing sites allow efficient device fabrication. We have also developed an elementary array of heterogeneous reaction sites and tested its performance by simultaneous incubation with the different specific antigens. © 2007 IEEE.

Note

Cited By (since 1996): 1Export Date: 26 August 2010Source: Scopus

URLhttp://www.scopus.com/inward/record.url?eid=2-s2.0-36049014275&partnerID=40&md5=ef1251c2552a72a09823a91c1bd21029
Citation Key341