In the present study we quantified volumetric brain asymmetries from computed tomography (CT) scans in 12 healthy dogs, using a semi-automated technique for assessing in vivo structure asymmetry. Volumetric assessment of asymmetrical cerebral lateral ventricle (ALV) was also investigated. Our results showed that seven dogs exhibited a right hemisphere significantly greater than the left, two dogs had a left-greater-than-right hemisphere asymmetry, and finally two dogs displayed no significant brain volumetric asymmetry. This right-biased hemispheric asymmetry supports data reported previously using post-mortem morphological studies in both dogs and other mammalian species. © 2010 Psychology Press.

Cited By :5Export Date: 17 July 2015CODEN: LATEFCorrespondence Address: Siniscalchi, M.; Department of Animal Production, University of Bari, Strada Provle per Casamassima, Km 3- 70010 Valenzano, Italy; email: m.siniscalchi@veterinaria.uniba.itReferences: Artmann, H., Grau, H., Adelmann, M., Schleiver, R., Reversible and non-reversible enlargement of cerebrospinal fluid spaces in anorexia nervosa (1985) Neuroradiology, 27, pp. 304-312;Chiu, H.C., Damasio, A.R., Human cerebral asymmetries evaluated by computed tomography (1980) Journal of Neurology and Neurosurgery Psychiatry, 43, pp. 873-878; Crow, T.J., Temporal lobe asymmetries as the key to the etiology of schizophrenia (1990) Schizophrenia Bulletin, 16, pp. 433-443; Denenberg, V.H., Hemispheric laterality in animals and the effects of early experience (1981) Behavioural and Brain Sciences, 4, pp. 1-21; Duara, R., Kushch, A., Gross-Glenn, K., Barker, W., Jallad, B., Pascal, S., Neuroanatomic differences between dyslexic and normal readers on magnetic resonance imaging scans (1991) Archives Neurology, 48, pp. 410-416; Geschwind, N., Behan, P., (1982) Left Handedness: Association With Immune Disease, Migraine, and Development Learning Disorder, 79, pp. 5097-5100. , Proceedings and Natural Academy of Science of the United States of America; Harcherik, D.F., Cohen, D.J., Ort, S., Paul, R., Shaywitz, B.A., Volkmar, F.R., Computed tomographic brain scanning in four neuropsychiatric disorders of childhood (1985) The American Journal of Psychiatry, 142, pp. 731-734; Kiroǧlu, Y., Karabulut, N., Oncel, C., Yagci, B., Sabir, N., Ozdemir, B., Cerebral lateral ventricular asymmetry on CT: How much asymmetry is representing pathology? (2008) Surgical and Radiological Anatomy, 30, pp. 249-255; Kolb, B., Sutherland, R.J., Nonneman, A.J., Whishaw, I.Q., Asymmetry in the cerebral hemispheres of the rat, mouse, rabbit, and cat: The right hemisphere is larger (1982) Experimental Neurology, 78, pp. 348-359; Macneilage, P.F., Rogers, L.J., Vallortigara, G., Origins of the left and right brain (2009) Scientific American, 301, pp. 60-67; Quaranta, A., Siniscalchi, M., Frate, A., Vallortigara, G., Paw preference in dogs: Relations between lateralised behaviour and immunity (2004) Behavioural Brain Research, 153, pp. 521-525; Quaranta, A., Siniscalchi, M., Vallortigara, G., Asymmetric tail-wagging responses by dogs to different emotive stimuli (2007) Current Biology, 17, pp. 199-201; Rosen, G.D., Sherman, G.F., Galaburda, A.M., Ontogenesis of neocortical asymmetry: A [3H] thymidine study (1991) Neuroscience, 41, pp. 779-790; Siniscalchi, M., Quaranta, A., Rogers, L.J., Hemispheric specialization in dogs for processing different acoustic stimuli (2008) PLoS One, 3, pp. e3349; Tan, U., Caliskan, S., Asymmetries in the cerebral dimensions and fissures of the dog (1987) International Journal of Neuroscience, 32, pp. 943-952; Tan, U., Caliskan, S., Allometry and asymmetry in the dog brain: The right hemisphere is heavier regardless of paw preference (1987) International Journal of Neuroscience, 35, pp. 189-194; Vallortigara, G., Rogers, L.J., Survival with an asymmetrical brain: Advantages and disadvantages of cerebral lateralisation (2005) Behaviour Brain Science, 28, pp. 575-589; Wang, Y.X., He, G.X., Tong, G.H., Wang, D.B., Xu, K.Y., Cerebral asymmetry in a selected Chinese population (1999) Australasian Radiology, 43, pp. 321-324; Wells, D.L., Millsopp, S., Lateralised behaviour in the domestic cat, Felis silvestris catus (2009) Animal Behaviour, 78, pp. 537-541; Zipursky, R.B., Lim, K.O., Pfefferbaum, A., Volumetric assessment of cerebral asymmetry from CT scans (1990) Psychiatry Research: Neuroimaging, 35, pp. 71-89