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Microdosimetry applied to nanosecond pulsed electric fields: a comparison on a single cell between real and ideal waveforms.

TitoloMicrodosimetry applied to nanosecond pulsed electric fields: a comparison on a single cell between real and ideal waveforms.
Tipo di pubblicazioneArticolo su Rivista peer-reviewed
Anno di Pubblicazione2011
AutoriMerla, Caterina, Paffi A., Apollonio F., Leveque P., and Liberti M.
RivistaConference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference
Volume2011
Paginazione302-305
ISSN1557170X
Parole chiaveanimal, Animals, article, Biological, biological model, cell membrane, Computer simulation, human, Humans, methodology, Models, physiology, Radiation Dosage, radiation dose, Radiation exposure, radiometry
Abstract

A microdosimetric analysis using ideal and real pulses was carried out in this paper. To perform this goal, authors employed an algorithm developed recently for nsPEF based on Laplace's equation and able to take into account cell compartment dispersivity. A comparison between biphasic real and ideal waveforms was carried out. The ideal pulse induced the highest pore density efficiency, hence evidencing that a device optimization to avoid waveform degradation and losses has a fundamental impact on the performances of the delivered pulses at the single cell level.

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URLhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84891683705&partnerID=40&md5=ff2ee4d16970dbe0cb6c496d72fbedad
Citation KeyMerla2011302