Sorry, you need to enable JavaScript to visit this website.

A wide-band bio-chip for real-time optical detection of bioelectromagnetic interactions with cells

TitoloA wide-band bio-chip for real-time optical detection of bioelectromagnetic interactions with cells
Tipo di pubblicazioneArticolo su Rivista peer-reviewed
Anno di Pubblicazione2018
AutoriMerla, Caterina, Liberti M., Marracino P., Muscat A., Azan A., Apollonio F., and Mir L.M.
RivistaScientific Reports
Volume8
ISSN20452322
Abstract

The analytical and numerical design, implementation, and experimental validation of a new grounded closed coplanar waveguide for wide-band electromagnetic exposures of cells and their optical detection in real-time is reported. The realized device fulfills high-quality requirements for novel bioelectromagnetic experiments, involving elevated temporal and spatial resolutions. Excellent performances in terms of matching bandwidth (less than -10 dB up to at least 3 GHz), emission (below 1 × 10-6 W/m2) and efficiency (around 1) have been obtained as revealed by both numerical simulations and experimental measurements. A low spatial electric field inhomogeneity (coefficient of variation of around 10 %) has been achieved within the cell solutions filling the polydimethylsiloxane reservoir of the conceived device. This original bio-chip based on the grounded closed coplanar waveguide concept opens new possibilities for the development of controlled experiments combining electromagnetic exposures and sophisticated imaging using optical spectroscopic techniques. © 2018 The Author(s).

Note

cited By 1

URLhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85044315706&doi=10.1038%2fs41598-018-23301-w&partnerID=40&md5=835a240803b25ccc83ab706fd12c7c7f
DOI10.1038/s41598-018-23301-w
Citation KeyMerla2018