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Broadband electrical detection of individual biological cells

TitoloBroadband electrical detection of individual biological cells
Tipo di pubblicazioneArticolo su Rivista peer-reviewed
Anno di Pubblicazione2014
AutoriNing, Y., Multari C., Luo X., Palego C., Cheng X., Hwang J.C.M., Denzi A., Merla Caterina, Apollonio F., and Liberti M.
RivistaIEEE Transactions on Microwave Theory and Techniques
Volume62
Paginazione1905-1911
Parole chiaveBiological cells, Biological engineering, Biological liquids, Biomedical transducers, Biosensors, Electrodes, Electrophoresis, Microstripes, Microwave measurement, Sensitivity
Abstract

To resolve the dilemma of cell clogging or solution parasitics encountered by Coulter counters and to evolve a general-purpose electrical detection technique, we used broadband microwave measurements to overcome electrode polarization, ac dielectrophoresis to precisely place cells between narrowly spaced electrodes, and relatively wide microfluidic channels to prevent cell clogging. This unique combination of approaches resulted in reproducible sensing of single Jurkat and HEK cells, both live and dead, of different cultures at different times. © 2014 IEEE.

Note

cited By 26

URLhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84930384810&doi=10.1109%2fTMTT.2014.2342660&partnerID=40&md5=a10f61927b71eee4c50ac994fd479880
DOI10.1109/TMTT.2014.2342660
Citation KeyNing20141905