Title | A 10-Ω high-voltage nanosecond pulse generator |
---|---|
Publication Type | Articolo su Rivista peer-reviewed |
Year of Publication | 2010 |
Authors | Merla, Caterina, S. Amari El, Kenaan M., Liberti M., Apollonio F., Arnaud-Cormos D., Couderc V., and Leveque P. |
Journal | IEEE Transactions on Microwave Theory and Techniques |
Volume | 58 |
Pagination | 4079-4085 |
Keywords | Biological experiments, cell culture, Electric switchgear, electroporation, Experimental characterization, FDTD simulations, Finite difference time domain method, Finite difference time-domain, Finite-difference time-domain models, High voltage, High-voltages, Linear regime, Low impedance, nanosecond generator, Nanosecond pulse generators, Numerical characterization, Optical instruments, Optical switches, Photoconductive semiconductor switches, Pulse generators, Semiconductor switches, Signal generators, Spice analysis, Time switches, Voltage sensor, Wide band frequencies |
Abstract | Devices used for biological experiments on cell cultures can present a low impedance. In this paper, a numerical and experimental characterization of a high-voltage, nanosecond-pulse, 10-Ω generator is proposed. The generator makes use of a combination of microstrip-line technology and laser-triggered photoconductive semiconductor switches that operate in the linear regime. A standard electroporation cuvette is used to load the generator. SPICE and finite-difference time-domain (FDTD) models of the whole setup (i.e., the generator and the cuvette) are developed. Numerical characterization is performed comparing SPICE analysis and FDTD simulations. Experimental characterization on a built prototype is carried out by means of a wideband frequency voltage sensor. A good level of consistency is obtained between the numerical and the experimental voltage intensities measured across the cuvette electrodes. © 2006 IEEE. |
Notes | cited By 27 |
URL | https://www.scopus.com/inward/record.uri?eid=2-s2.0-78650419540&doi=10.1109%2fTMTT.2010.2086470&partnerID=40&md5=c10256cbafe5fa4442569d3989af9a18 |
DOI | 10.1109/TMTT.2010.2086470 |
Citation Key | Merla20104079 |