Title | Microdosimetry applied to nanosecond pulsed electric fields: A comparison on a single cell between real and ideal waveforms |
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Publication Type | Presentazione a Congresso |
Year of Publication | 2011 |
Authors | Merla, Caterina, Paffi A., Apollonio F., Leveque P., and Liberti M. |
Conference Name | Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS |
Keywords | Biphasic, Cells, Device optimization, dispersivity, Electric fields, Laplace equation, Laplace transforms, Laplace's equations, Micro-dosimetry, Nanosecond pulsed electric fields, Pore densities, Single cells, Single-cell level, Wave forms, Waveform degradation |
Abstract | A microdosimetric analysis using ideal and real pulses was carried out in this paper. To perform this goal, authors employed an algorithm developed recently for nsPEF based on Laplace's equation and able to take into account cell compartment dispersivity. A comparison between biphasic real and ideal waveforms was carried out. The ideal pulse induced the highest pore density efficiency, hence evidencing that a device optimization to avoid waveform degradation and losses has a fundamental impact on the performances of the delivered pulses at the single cell level. © 2011 IEEE. |
URL | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84055212372&doi=10.1109%2fIEMBS.2011.6090079&partnerID=40&md5=a8572219e0b93dec6b08e2baccd5f2ac |
DOI | 10.1109/IEMBS.2011.6090079 |
Citation Key | Merla2011302 |