| Title | Fast, compact and label-free electrical detection of live and dead single cells |
|---|---|
| Publication Type | Presentazione a Congresso |
| Year of Publication | 2013 |
| Authors | Ning, Y., Multari C.R., Luo X., Merla Caterina, Palego C., Cheng X., and Hwang J.C.M. |
| Conference Name | 2013 IEEE MTT-S International Microwave Workshop Series on RF and Wireless Technologies for Biomedical and Healthcare Applications, IMWS-BIO 2013 - Proceedings |
| Keywords | Bio-impedance, Biological cells, Biosensors, Cell manipulation, Cells, cytology, Electrical detection, Health Care, Impedance match, Microfluidics, Microsensors, molecular biology, Reflectometry, Single-cell level, Solution effects, Wireless telecommunication systems |
| Abstract | Using a novel broadband microchamber, electrical detection of live and dead single cells was demonstrated. Tests on Jurkat cells showed that live cells had lower resistance but higher capacitance than that of dead cells. The test results were compared with the limited literature on broadband electrical detection of single cells and the discrepancies, both qualitative and quantitative, were discussed. These results indicate that, while broadband electrical detection at the single-cell level is becoming feasible, many challenges remain in impedance match, calibration, sensitivity, cell manipulation, solution effect and modeling. © 2013 IEEE. |
| URL | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84897494841&doi=10.1109%2fIMWS-BIO.2013.6756250&partnerID=40&md5=de3bc745f6b9d81acec663e84bb06f1c |
| DOI | 10.1109/IMWS-BIO.2013.6756250 |
| Citation Key | Ning2013 |
