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Broadband microchamber for electrical detection of live and dead biological cells

TitleBroadband microchamber for electrical detection of live and dead biological cells
Publication TypePresentazione a Congresso
Year of Publication2013
AuthorsPalego, C., Merla Caterina, Ning Y., Multari C.R., Cheng X., Molinero D.G., Ding G., Luo X., and Hwang J.C.M.
Conference NameIEEE MTT-S International Microwave Symposium Digest
KeywordsBio-impedance, Biological cells, Biosensors, Broadband impedance, Cells, Coplanar waveguides, cytology, Electrical detection, Fabrication, Fluidic devices, Micro-chambers, Microchannels, Microfluidic channel, Microfluidics, Microsensors, Quartz, Reflectometry, Silicones, Time and frequency domains
Abstract

A novel broadband microchamber for electrical detection of live and dead biological cells was designed, fabricated and tested. The microchamber was formed between a gold coplanar waveguide fabricated on a quartz slide and the microfluidic channels fabricated in a polydimethylsiloxane cover. The coplanar waveguide allowed broadband impedance matching and efficient cell trapping. The microfluidic channels delivered single cells precisely. Tests on Jurkat cells in both time and frequency domains showed that live cells had lower resistance but higher capacitance than that of dead cells. © 2013 IEEE.

URLhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84893254170&doi=10.1109%2fMWSYM.2013.6697355&partnerID=40&md5=1615dd0059b3e87533661ec783fc79aa
DOI10.1109/MWSYM.2013.6697355
Citation KeyPalego2013