Title | Frequency spectra of induced transmembrane potential correlate with nanosecond bipolar pulse cancellation of electropermeabilization |
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Publication Type | Presentazione a Congresso |
Year of Publication | 2017 |
Authors | Merla, Caterina, Pakhomov A.G., and Vernier P.T. |
Conference Name | SMACD 2017 - 14th International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design |
Keywords | Bioelectric potentials, Bipolar pulse, Calcium, Cancellation effects, Electric pulse, Electropermeabilization, Frequency spectra, Integrated circuit manufacture, Micro-dosimetry, Prediction methods, Spectroscopy, Spectrum Analysis, Transmembrane potentials |
Abstract | A simple prediction method for the bipolar pulse cancellation effect is proposed, based on analysis of single-cell transmembrane potential frequency spectra for a variety of unipolar and bipolar input signals in the nanosecond and microsecond time scales. Our evaluations are in good agreement with experimental results for electropermeabilization-induced Ca2+ influx using 300 ns, 750 kV/m pulses. © 2017 IEEE. |
URL | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85027494876&doi=10.1109%2fSMACD.2017.7981604&partnerID=40&md5=f6f5d49c5fb2cb0b69869375c00b8628 |
DOI | 10.1109/SMACD.2017.7981604 |
Citation Key | Merla2017 |