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Patterning polyacrylamide hydrogels by soft lithography

TitlePatterning polyacrylamide hydrogels by soft lithography
Publication TypeArticolo su Rivista peer-reviewed
Year of Publication2005
AuthorsDi Benedetto, Francesca, Biasco A., Pisignano D., and Cingolani R.
JournalNanotechnology
Volume16
PaginationS165-S170
ISSN09574484
KeywordsAcrylics, biocompatibility, Capillarity, Hydrogel patterns, Hydrogels, Lithography, Microstructure, Molding, Poly(acrylamides), polymerization, Room-temperature molding, Soft lithography, Solvents, Surface treatment
Abstract

Because of the chemical flexibility and broad range of applications of hydrogels, the direct patterning of biocompatible gel structures certainly deserves to be fully explored. This paper describes a method of creating hydrogel patterns of poly(acrylamide) by soft lithography. Room-temperature moulding is employed in order to directly transfer microstructures into poly(acrylamide), in a parallel manner up to a resolution of 2 μm. During the imprinting process, the gel at the liquid state flows into the shape of the stamp, driven by a combination of spontaneous capillarity and pressure-induced transport, without using any photon-beam, solvent, and chemical surface treatment. After the polymerization of the system, a negative copy of the stamp pattern is therefore frozen on the target material surface. © 2005 IOP Publishing Ltd.

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URLhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-24144432811&doi=10.1088%2f0957-4484%2f16%2f5%2f006&partnerID=40&md5=72199b22b75dc8574a8a13e41b182e57
DOI10.1088/0957-4484/16/5/006
Citation KeyDiBenedetto2005